Extract Drugs from Differential Expression Data from LINCS Database


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Documentation for package ‘DFD’ version 0.2.0

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convert_id Convert Gene Symbols to ENTREZ IDs
filter_drugs Re-rank drugs based on the number of targets
get_drugs Get Drugs associated with the differential expression profile
get_pert_by_type Filter the drug based on the tested cell-line
parse_perts Parse the perturbagens to find out their frequency of occurrence.
plot_activities Visualise the number of perturbagens and the top activities
prepare_ids Prepare IDs for CMAP Search
read_id Read Gene Symbols from CSV file into up and down regulated lists
run_pipeline Run the main pipeline for getting drugs from differentail expression profile