DTSEA: Drug Target Set Enrichment Analysis
It is a novel tool used to identify the candidate drugs against a particular disease based on the drug target set enrichment analysis. It assumes the most effective drugs are those with a closer affinity in the protein-protein interaction network to the specified disease. (See Gómez-Carballa et al. (2022) <doi:10.1016/j.envres.2022.112890> and Feng et al. (2022) <doi:10.7150/ijms.67815> for disease expression profiles; see Wishart et al. (2018) <doi:10.1093/nar/gkx1037> and Gaulton et al. (2017) <doi:10.1093/nar/gkw1074> for drug target information; see Kanehisa et al. (2021) <doi:10.1093/nar/gkaa970> for the details of KEGG database.)
| Version: |
0.0.3 |
| Depends: |
R (≥ 4.0.0) |
| Imports: |
dplyr, fgsea, igraph, magrittr, tibble, tidyr, BiocParallel, stringr |
| Suggests: |
knitr, rmarkdown |
| Published: |
2022-11-06 |
| DOI: |
10.32614/CRAN.package.DTSEA |
| Author: |
Junwei Han [aut, cre, cph],
Yinchun Su [aut] |
| Maintainer: |
Junwei Han <hanjunwei1981 at 163.com> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: |
no |
| Materials: |
README NEWS |
| CRAN checks: |
DTSEA results |
Documentation:
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