Encodes several methods for performing Mendelian randomization analyses with summarized data. Summarized data on genetic associations with the exposure and with the outcome can be obtained from large consortia. These data can be used for obtaining causal estimates using instrumental variable methods.
Version: | 0.10.0 |
Depends: | R (≥ 3.0.1), methods |
Imports: | knitr, rmarkdown, plotly (≥ 3.6.0), ggplot2 (≥ 1.0.1), robustbase (≥ 0.92-6), Matrix (≥ 1.2), iterpc (≥ 0.3), quantreg (≥ 5.01), rjson, glmnet, numDeriv, Rcpp |
LinkingTo: | Rcpp, RcppArmadillo |
Published: | 2024-04-12 |
DOI: | 10.32614/CRAN.package.MendelianRandomization |
Author: | Stephen Burgess [aut, cre], Olena Yavorska [aut], James Staley [ctb], Fernando Hartwig [ctb], Jim Broadbent [ctb], Christopher Foley [ctb], Andrew Grant [ctb], Amy Mason [ctb], Ting Ye [ctb], Haoran Xue [ctb], Zhaotong Lin [ctb], Siqi Xu [ctb], Ashish Patel [ctb], Hyunseung Kang [ctb], Sheng Wang [ctb], Ville Karhunen [ctb] |
Maintainer: | Stephen Burgess <sb452 at medschl.cam.ac.uk> |
License: | GPL-2 | GPL-3 |
NeedsCompilation: | yes |
Materials: | NEWS |
In views: | CausalInference, MetaAnalysis |
CRAN checks: | MendelianRandomization results |
Reference manual: | MendelianRandomization.pdf |
Vignettes: |
Mendelian randomization vignette |
Package source: | MendelianRandomization_0.10.0.tar.gz |
Windows binaries: | r-devel: MendelianRandomization_0.10.0.zip, r-release: MendelianRandomization_0.10.0.zip, r-oldrel: MendelianRandomization_0.10.0.zip |
macOS binaries: | r-release (arm64): MendelianRandomization_0.10.0.tgz, r-oldrel (arm64): MendelianRandomization_0.10.0.tgz, r-release (x86_64): MendelianRandomization_0.10.0.tgz, r-oldrel (x86_64): MendelianRandomization_0.10.0.tgz |
Old sources: | MendelianRandomization archive |
Reverse suggests: | mrbayes |
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