cdtmbnma: Component, Dose, and Time Network Meta-Analysis with
Dose-Dependent Interactions
Bayesian component model-based network meta-analysis for treatment
combinations with explicit component dose-response and dose-dependent
interaction surfaces. The main interface fits single-timepoint arm-level
networks with continuous or binary outcomes, any number of components,
additive, bilinear, or saturating pairwise interactions, study-level random
effects, and prediction at unobserved dose combinations. A stage-one
longitudinal interface fits a two-component exponential time-course model
with a bilinear interaction on the asymptote. Estimation uses 'Stan' through
'cmdstanr' or 'rstan'. Methods are described in Welton et al. (2009)
<doi:10.1093/aje/kwp014>, Mawdsley et al. (2016) <doi:10.1002/psp4.12091>,
Wicha et al. (2017) <doi:10.1038/s41467-017-01929-y>, and Pedder et al.
(2019) <doi:10.1002/jrsm.1351>.
| Version: |
0.2.1 |
| Depends: |
R (≥ 4.1.0) |
| Imports: |
posterior, stats, graphics, grDevices, utils |
| Suggests: |
cmdstanr, rstan, testthat (≥ 3.0.0), knitr, rmarkdown, loo |
| Published: |
2026-07-22 |
| DOI: |
10.32614/CRAN.package.cdtmbnma (may not be active yet) |
| Author: |
Tyler Pitre [aut, cre] |
| Maintainer: |
Tyler Pitre <pitretmed at gmail.com> |
| License: |
MIT + file LICENSE |
| NeedsCompilation: |
no |
| SystemRequirements: |
A working Stan backend through cmdstanr/CmdStan or
rstan. |
| Additional_repositories: |
https://stan-dev.r-universe.dev |
| Citation: |
cdtmbnma citation info |
| Materials: |
README, NEWS |
| CRAN checks: |
cdtmbnma results |
Documentation:
Downloads:
Linking:
Please use the canonical form
https://CRAN.R-project.org/package=cdtmbnma
to link to this page.