hpsreg: Regression for Hierarchically Ordered Clinical Outcomes via
Pairwise Comparisons (Bradley-Terry-Davidson Model)
Provides regression for hierarchically ordered clinical
outcomes via pairwise comparisons, using a covariate-adjusted
Davidson (Bradley-Terry with ties) model with U-statistic sandwich
standard errors. A hierarchy of outcomes (binary, ordinal, continuous,
and time-to-event, with eligibility guards and tie margins) is
defined; all pairs of subjects are scored lexicographically; and the
resulting win / loss / tie data are analysed. Unadjusted win statistics
(net benefit, win ratio, win odds), diagnostics, and a worked example
based on outcomes after allogeneic stem cell transplant are also
provided. The computational engine is written in 'C++' using 'Rcpp'
and 'RcppEigen'.
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