Package {robusttseq}


Title: Robust Statistical Methods with Huber Estimators
Version: 0.1.0
Author: Nair Gonzalez Sotomayor [aut, cre], Aquiles Enrique Darghan Contreras [aut]
Maintainer: Nair Gonzalez Sotomayor <njgonzalezs@unal.edu.co>
Description: Provides robust statistical methods for analyzing numeric data, including robust estimation of location and scale using Huber M-estimators and a robust two-sample t-test. Methods are based on Huber (1981, ISBN:0471418056) "Robust Statistics" and Smyth (2004) <doi:10.2202/1544-6115.1027>.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.3.3
Imports: limma, stats
NeedsCompilation: no
Packaged: 2026-05-30 17:09:41 UTC; root
Repository: CRAN
Date/Publication: 2026-06-03 14:10:07 UTC

Huber M-estimator for location and scale

Description

Computes robust estimates of mean (mu) and scale (sigma) using Huber's M-estimator.

Usage

huber_estimation(x, c = 1.345, tol = 1e-06, max_iter = 100)

Arguments

x

Numeric vector of observations.

c

Tuning constant (default 1.345). Larger values make the estimator closer to the mean, smaller values make it more robust.

tol

Convergence tolerance (default 1e-6).

max_iter

Maximum number of iterations (default 100).

Value

A list with two elements:

mu

Estimated robust mean

sigma

Estimated robust scale (standard deviation)

Examples

set.seed(123)
x <- c(rnorm(100), 10)  # outlier at 10
huber_estimation(x)


Robust Huber-Moderated t-Test for Gene Expression

Description

Performs a moderated two-sample t-test on count data using Huber M-estimators and empirical Bayes variance shrinkage (via limma::squeezeVar).

Usage

robust_huber_moderated(counts, group, c_huber = 1.345, robust_prior = TRUE)

Arguments

counts

Numeric matrix of counts (genes in rows, samples in columns).

group

Factor indicating group membership for each column/sample.

c_huber

Tuning constant for Huber estimator (default 1.345).

robust_prior

Logical; if TRUE, uses a robust empirical Bayes prior (default TRUE).

Value

Numeric vector of p-values, one per gene.

Examples


library(limma)
counts <- matrix(rpois(200, lambda = 10), nrow = 20)
group <- factor(rep(c("A", "B"), each = 5))
pvals <- robust_huber_moderated(counts, group)



Two-Sample Robust t-Test (Huber)

Description

Performs a robust two-sample t-test using Huber M-estimators for location and scale.

Usage

robust_t_test(x, y, c = 1.345)

Arguments

x

Numeric vector of sample 1.

y

Numeric vector of sample 2.

c

Tuning constant for Huber estimator (default 1.345).

Value

An object of class "htest" similar to t.test.

Examples

set.seed(123)
x <- rnorm(30, mean = 5)
y <- rnorm(35, mean = 6)
robust_t_test(x, y)