Mode
Mode contains buttons for switching between Mouse Controls used for viewing mode (View, on by default) and those for performing actions including Border drawing and Foci creation.  The mouse controls for rotating, panning and zooming a structure in the Viewing Area are still active in Border and Foci modes. Information on mouse and key strokes for using the mode tools are available as Tooltips.
Border button opens the border drawing, editing, and ROI tools at the bottom of the Toolbar:
Foci button opens the focus creation and editing tools at the bottom of the Toolbar: